For COVID-19 vaccine updates, please review our information guide. For patient eligibility and scheduling availability, please visit VaccineTogetherNY.org.

Faculty Publications

Recently Added Publications:

Somatic mutations and cell identity linked by Genotyping of Transcriptomes

Anna (Seung Ha) Nam, MD

Somatic mutations and cell identity linked by Genotyping of Transcriptomes

Nature. 2019 Jul;571(7765):355-360. 

Nam AS, Kim KT, Chaligne R, Izzo F, Ang C, Taylor J, Myers RM, Abu-Zeinah G, Brand R, Omans ND, Alonso A, Sheridan C, Mariani M, Dai X, Harrington E, Pastore A, Cubillos-Ruiz JR, Tam W, Hoffman R, Rabadan R, Scandura JM, Abdel-Wahab O, Smibert P, Landau DA.

PMID: 31270458; PMCID: PMC6782071

Read More

Multiplex Immunofluorescence in Formalin-Fixed Paraffin-Embedded Tumor Tissue to Identify Single-Cell-Level PI3K Pathway Activation

Massimo Loda, MD

Multiplex Immunofluorescence in Formalin-Fixed Paraffin-Embedded Tumor Tissue to Identify Single-Cell-Level PI3K Pathway Activation

Clin Cancer Res. 2020 Sep 10. 

Stopsack KH, Huang Y, Tyekucheva S, Gerke TA, Bango C, Elfandy H, Bowden M, Penney KL, Roberts TM, Parmigiani G, Kantoff PW, Mucci LA, Loda M.

PMID: 32913135.

Read More

Integrating genetic and non-genetic determinants of cancer evolution by single-cell multi-omics

Anna (Seung Ha) Nam, MD

Integrating genetic and non-genetic determinants of cancer evolution by single-cell multi-omics

Nat Rev Genet. 2020 Aug 17. Review Article.

Nam AS, Chaligne R, Landau DA.

Read More

Derepression of a single miRNA target causes female infertility in mice

Benjamin Kleaveland, MD, PhD

Derepression of a single miRNA target causes female infertility in mice

Kleaveland BStefano J, Hong S-J, Bartel DP.

Manuscript in preparation.

Read More

Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention

Massimo Loda, MD

Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention

Adv Drug Deliv Rev. 2020 Jul 23:S0169-409X(20)30097-1. 

Butler LM, Perone Y, Dehairs J, Lupien LE, de Laat V, Talebi A, Loda M, Kinlaw WB, Swinnen JV.

PMID: 32711004

Read More

DNA methylation disruption reshapes the hematopoietic differentiation landscape

Anna (Seung Ha) Nam, MD

DNA methylation disruption reshapes the hematopoietic differentiation landscape

Nat Genet. 2020 Apr;52(4):378-387. 

Izzo F, Lee SC, Poran A, Chaligne R, Gaiti F, Gross B, Murali RR, Deochand SD, Ang C, Jones PW, Nam AS, Kim KT, Kothen-Hill S, Schulman RC, Ki M, Lhoumaud P, Skok JA, Viny AD, Levine RL, Kenigsberg E, Abdel-Wahab O, Landau DA.

PMID: 32203468; PMCID: PMC7216752

Read More

The complexity of the serine glycine one-carbon pathway in cancer.

Maria Diaz-Meco Conde, PhD, Jorge Moscat-Guillen, PhD

The complexity of the serine glycine one-carbon pathway in cancer.

J Cell Biol. 2020 Jan 6;219(1).

Reina-Campos M, Diaz-Meco MT, Moscat J.

PMID: 31690618

Read More

Serrated Colorectal Cancer: The Road Less Travelled?

Jorge Moscat-Guillen, PhD

Serrated Colorectal Cancer: The Road Less Travelled?

Trends Cancer. 2019 Nov;5(11):742-754.

Nakanishi Y, Diaz-Meco MT, Moscat J.

PMID: 31735291; PMCID: PMC6894428

Read More

High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program

Massimo Loda, MD

High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program

Nat Commun. 2019 Sep 25;10(1):4358. 

Labbé DP, Zadra G, Yang M, Reyes JM, Lin CY, Cacciatore S, Ebot EM, Creech AL, Giunchi F, Fiorentino M, Elfandy H, Syamala S, Karoly ED, Alshalalfa M, Erho N, Ross A, Schaeffer EM, Gibb EA, Takhar M, Den RB, Lehrer J, Karnes RJ, Freedland SJ, Davicioni E, Spratt DE, Ellis L, Jaffe JD, DʼAmico AV, Kantoff PW, Bradner JE, Mucci LA, Chavarro JE, Loda M, Brown M.

PMID: 31554818; PMCID: PMC6761092.

Read More

The Dual Roles of the Atypical Protein Kinase Cs in Cancer

Maria Diaz-Meco Conde, PhD, Jorge Moscat-Guillen, PhD

The Dual Roles of the Atypical Protein Kinase Cs in Cancer

Cancer Cell. 2019 Sep 16;36(3):218-235. 

Reina-Campos M, Diaz-Meco MT, Moscat J.

PMID: 31474570; PMCID: PMC6751000

Read More

HDAC7 regulates histone 3 lysine 27 acetylation and transcriptional activity at super-enhancer-associated genes in breast cancer stem cells

Tan Ince, MD, PhD

HDAC7 regulates histone 3 lysine 27 acetylation and transcriptional activity at super-enhancer-associated genes in breast cancer stem cells

Oncogene. 2019 Sep;38(39):6599-6614.

Caslini C, Hong S, Ban YJ, Chen XS, Ince TA.

PMID: 31375747

Read More

Exploring tumor clonal evolution in bone marrow of patients with diffuse large B-cell lymphoma by deep IGH sequencing and its potential relevance in relapse

Anna (Seung Ha) Nam, MD

Exploring tumor clonal evolution in bone marrow of patients with diffuse large B-cell lymphoma by deep IGH sequencing and its potential relevance in relapse

Blood Cancer J. 2019 Aug 21;9(9):69. 

Ma J, Redmond D, Miyaguchi A, Nam AS, Nie K, Mathew S, Elemento O, Tam W.

PMID: 31434873; PMCID: PMC6704167

Read More

Ovarian Cancer Treatment Stratification Using Ex Vivo Drug Sensitivity Testing

Tan Ince, MD, PhD

Ovarian Cancer Treatment Stratification Using Ex Vivo Drug Sensitivity Testing

Anticancer Res. 2019 Aug;39(8):4023-4030.

Lohse I, Azzam DJ, Al-Ali H, Volmar CH, Brothers SP, Ince TA, Wahlestedt C.

PMID: 31366484

Read More

Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer.

Maria Diaz-Meco Conde, PhD

Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer.

Cancer Cell. 2019 Mar 18;35(3):385-400.

Reina-Campos M, Linares JF, Duran A, Cordes T, L'Hermitte A, Badur MG, Bhangoo MS, Thorson PK, Richards A, Rooslid T, Garcia-Olmo DC, Nam-Cha SY, Salinas-Sanchez AS, Eng K, Beltran H, Scott DA, Metallo CM, Moscat J, Diaz-Meco MT.

PMID: 30827887; PMCID: PMC6424636

Read More

Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer

Jorge Moscat-Guillen, PhD

Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer

Cancer Cell. 2019 Mar 18;35(3):385-400.

Reina-Campos M, Linares JF, Duran A, Cordes T, L'Hermitte A, Badur MG, Bhangoo MS, Thorson PK, Richards A, Rooslid T, Garcia-Olmo DC, Nam-Cha SY, Salinas-Sanchez AS, Eng K, Beltran H, Scott DA, Metallo CM, Moscat J, Diaz-Meco MT.  

PMID: 30827887; PMCID: PMC6424636

Read More

Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer

Massimo Loda, MD

Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer

Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):631-640. 

Zadra G, Ribeiro CF, Chetta P, Ho Y, Cacciatore S, Gao X, Syamala S, Bango C, Photopoulos C, Huang Y, Tyekucheva S, Bastos DC, Tchaicha J, Lawney B, Uo T, D'Anello L, Csibi A, Kalekar R, Larimer B, Ellis L, Butler LM, Morrissey C, McGovern K, Palombella VJ, Kutok JL, Mahmood U, Bosari S, Adams J, Peluso S, Dehm SM, Plymate SR, Loda M.

PMID: 30578319; PMCID: PMC6329966.

Erratum in: Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18893. 

Read More

Simultaneous Loss of Both Atypical Protein Kinase C Genes in the Intestinal Epithelium Drives Serrated Intestinal Cancer by Impairing Immunosurveillance

Jorge Moscat-Guillen, PhD

Simultaneous Loss of Both Atypical Protein Kinase C Genes in the Intestinal Epithelium Drives Serrated Intestinal Cancer by Impairing Immunosurveillance

Immunity. 2018 Dec 18;49(6):1132-1147.e7.

Nakanishi Y, Duran A, L'Hermitte A, Shelton PM, Nakanishi N, Reina-Campos M, Huang J, Soldevila F, Baaten BJG, Tauriello DVF, Castilla EA, Bhangoo MS, Bao F, Sigal D, Diaz-Meco MT, Moscat J.

PMID: 30552022; PMCID: PMC6301096

Read More

Dual Src and MEK Inhibition Decreases Ovarian Cancer Growth and Targets Tumor Initiating Stem-Like Cells

Tan Ince, MD, PhD

Dual Src and MEK Inhibition Decreases Ovarian Cancer Growth and Targets Tumor Initiating Stem-Like Cells

Clin Cancer Res. 2018 Oct 1;24(19):4874-4886. 

Simpkins F, Jang K, Yoon H, Hew KE, Kim M, Azzam DJ, Sun J, Zhao D, Ince TA, Liu W, Guo W, Wei Z, Zhang G, Mills GB, Slingerland JM.

PMID: 29959144; PMCID: PMC6557165

Read More

Surf4 (Erv29p) binds amino-terminal tripeptide motifs of soluble cargo proteins with different affinities, enabling prioritization of their exit from the endoplasmic reticulum

Anna (Seung Ha) Nam, MD

Surf4 (Erv29p) binds amino-terminal tripeptide motifs of soluble cargo proteins with different affinities, enabling prioritization of their exit from the endoplasmic reticulum

PLoS Biol. 2018 Aug 7;16(8):e2005140.

Yin Y, Garcia MR, Novak AJ, Saunders AM, Ank RS, Nam AS, Fisher LW.

PMID: 30086131; PMCID: PMC6097701

Read More

Metabolic reprogramming of the tumor microenvironment by p62 and its partners

Maria Diaz-Meco Conde, PhD

Metabolic reprogramming of the tumor microenvironment by p62 and its partners

Biochim Biophys Acta Rev Cancer. 2018 Aug;1870(1):88-95.

Reina-Campos M, Shelton PM, Diaz-Meco MT, Moscat J.

PMID: 29702207; PMCID: PMC6193563

Read More

Weill Cornell Medicine Pathology & Laboratory Medicine 1300 York Avenue New York, NY 10065 Phone: (212) 746-6464 Fax: (212) 746-8192