January 19, 2024
Congratulations to Drs. Amy Chadburn, Syed Hoda, Jose Jessurun, and Cynthia Magro on being recognized as a 2024 Top Doctor by Castle Connolly, which are peer-nominated, for excellence in Medicine.
January 12, 2024
Stromal cells, found in all organs, contribute to wound-healing, blood vessel formation and structural support for tissues. Scientists know that tumors often co-opt stromal cells to create a more supportive molecular environment for tumor growth and survival. But their precise roles in different cancers are only beginning to be delineated.
December 13, 2023
Hard-to-detect colorectal pre-cancerous lesions known as serrated polyps, and the aggressive tumors that develop from them, depend heavily on the ramped-up production of cholesterol, according to a preclinical study from researchers at Weill Cornell Medicine. The finding points to the possibility of using cholesterol-lowering drugs to prevent or treat such tumors.
November 28, 2023
Article originally published by Mark Johnson in The Washington Post, 11/28/23. Scientists have discovered a new type of stem cell in the spine that appears crucial to resolving a long-standing mystery: why far more cancer cells spread to the spine than to other bones in the body.
November 15, 2023
A team at Weill Cornell Medicine has mapped the location and spatial features of blood-forming cells within human bone marrow. Their findings confirm hypotheses about the anatomy of this tissue and provide a powerful new means to study diseases, ranging from noncancerous conditions, such as sickle cell anemia, to malignant conditions, such as acute leukemia, that affect bone marrow.
October 25, 2023
Certain gut-dwelling fungi flourish in severe cases of COVID-19, amplifying the excessive inflammation that drives this disease while also causing long-lasting changes in the immune system, according to a new study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian. This discovery identifies a group of patients who may benefit from specialized, but yet-to-be determined treatments.
September 25, 2023
Researchers at Weill Cornell Medicine have discovered that radiation therapy combined with two types of immunotherapy—one that boosts T cells, and another that boosts dendritic cells—can control tumors in preclinical models of triple negative breast cancer, a cancer type that’s typically resistant to immunotherapy alone.
September 20, 2023
Craniosynostosis, the premature fusion of the top of the skull in infants, is caused by an abnormal excess of a previously unknown type of bone-forming stem cell, according to a preclinical study led by researchers at Weill Cornell Medicine.
September 13, 2023
The vertebral bones that form the spine are derived from a distinct type of stem cell that secretes a protein favoring tumor metastases, according to a study led by researchers at Weill Cornell Medicine. The discovery opens up a new line of research on spinal disorders, helps explain why solid tumors so often spread to the spine, and could lead to new orthopedic and cancer treatments. In the study, published Sept. 13 in Nature, the researchers discovered that vertebral bone is derived from a stem cell that is different from other bone-making stem cells. Using bone-like “organoids” made from...
August 19, 2023
Severe COVID-19 infection triggers changes that affect gene expression in immune system stem cells, causing long-lasting alterations in the body’s immune response, according to a new study by Weill Cornell Medicine and Jackson Laboratory investigators. The finding could help explain symptoms of prolonged inflammation and “long COVID” in people who have had the disease.The research team, led by Dr. Steven Josefowicz, an associate professor of pathology and laboratory medicine at Weill Cornell Medicine, and Dr. Duygu Ucar, an associate professor at Jackson Laboratory for Genomic Medicine,...