Cell Cycle

Principal Investigator: 
Selina Chen-Kiang, Ph.D.

Our goal is to understand the mechanism for cell cycle control of immunity and hematologic malignancies and to translate this knowledge into novel cell cycle-based cancer therapy. Following our discovery that CDK4/CDK6 control B cell immunity, we are investigating CDK control of cancer metabolism and defining genes that mediate clinical response to our hypothesis- driven therapy targeting CDK4/CDK6 in lymphoma and myeloma.

Active Projects

  • Cell cycle control of B cell hemostasis and plasma cell differentiation
  • Cell cycle control of cancer metabolism in lymphoma and myeloma
  • Defining the mechanism of resistance to therapeutic CDK4/CDK6-based therapy by integrated functional genomics

Grants

PI: Selina Chen-Kiang, Ph.D.
National Cancer Institute

PI: Selina Chen-Kiang, Ph.D.
The Leukemia & Lymphoma Society Mantle Cell Lymphoma Research Initiative

PI: Selina Chen-Kiang, Ph.D.
National Cancer Institute

PI: Selina Chen-Kiang, Ph.D.
American Society of Hematology Bridge Grant

Lab Team

Cell Cycle Lab Team

Contact Information

Selina Chen-Kiang, Ph.D.
Professor of Pathology and Laboratory Medicine
Weill Cornell Medical College

1300 York Avenue
C-316
New York, NY 10065
Phone: 
212-746-6442
Fax: 
212-746-7996

Pathology & Laboratory Medicine 1300 York Avenue New York, NY 10065 Phone: (212) 746-6464
Surgical Pathology: (212) 746-2700