Contact Information
Selina Chen-Kiang, Ph.D.
Professor of Pathology and Laboratory Medicine
Weill Cornell Medical College
1300 York Avenue
C-316
New York, NY 10065
Our goal is to understand the mechanism for cell cycle control of immunity and hematologic malignancies and to translate this knowledge into novel cell cycle-based cancer therapy. Following our discovery that CDK4/CDK6 control B cell immunity, we are investigating CDK control of cancer metabolism and defining genes that mediate clinical response to our hypothesis- driven therapy targeting CDK4/CDK6 in lymphoma and myeloma.
Active Projects
- Cell cycle control of B cell hemostasis and plasma cell differentiation
- Cell cycle control of cancer metabolism in lymphoma and myeloma
- Defining the mechanism of resistance to therapeutic CDK4/CDK6-based therapy by integrated functional genomics