Newly Awarded Grants

NIH Support for Scientific Conferences (R13)

Title: The 22nd international conference on Kaposi's sarcoma-associated herpes virus and related agents
Principal Investigator: Ethel Cesarman, MD, PhD
Period of Support: 04/09/2019 – 03/31/2020
Total Direct Costs: $8,000

Inter-campus Seed Grant 

Title: Disruption of protein synthesis by cytoplasmic inclusions of RNA-binding proteins drives cytotoxicity and neurodegeneration in ALS/FTD
Principal Investigator: Jessica Tyler, PhD & Slu Sylvia Lee, PhD (Cornell, Ithaca)
Period of Support: 07/01/2019 – 06/30/2020
Total Direct Costs: $75,000

LLS Career Development Program Award

Title: Mechanisms of aberrant DNA double-strand break repair leading to lymphoid malignancy
Principal Investigator: Chun-Chin Chen, PhD (Postdoc, Barry Sleckman Lab)
Period of Support: 07/01/2019 – 06/30/2022
Total Direct Costs: $171,429

National Institutes of Health Research Grant (R01)

Title: Role of novel onco-histone mutations in B-cell malignancies
Principal Investigator: Ethel Cesarman, MD, PhD & Charles David Allis, PhD (Rockefeller)
Period of Support: 08/01/2019 – 07/31/2024
Total Direct Costs: $630,707

HHV-6 Foundation Grant

Title: HHV-6 in the lymphoma microenvironment
Principal Investigator: Genevieve Crane, MD, PhD & Ethel Cesarman, MD, PhD
Period of Support: 08/06/2019 – 08/05/2020
Total Direct Costs: $9,309

NIH High Priority, Short-Term Project Award (R56)

Title: Mechanisms underlying integrated stress response induced inflammation
Principal Investigator: Jihye Paik, PhD     
Period of Support: 09/01/2019 – 08/31/2020
Total Direct Costs: $250,000

Pershing Square Sohn Cancer Research Alliance

Title: Targeting skeletal stem cells to treat tumor-induced osteolysis
Principal Investigator: Matthew Greenblatt, MD PhD
Period of Support: 07/01/2019-06/30/2022
Total Direct Costs: $545,454

MSK Lymphoma SPORE Career Enhancement Program

Title: Targeting metabolic vulnerabilities in primary effusion lymphoma using the novel nucleoside analog (6-ETI)
Principal Investigator: Jouliana Sadek, PhD (Instructor, Ethel Cesarman Lab)
Period of Support: 08/01/2019-07/31/2020
Total Direct Costs: $50,000

National Institutes of Health (R01)

Title: Defining molecular determinants of lineage plasticity as a mechanism of treatment resistance in prostate cancer
Principal Investigator: David S. Rickman, PhD
Period of Support: 08/01/2019-07/31/2024
Total Direct Costs: $1,443,165

National Institutes of Health

Title: Recipient epidemiology and donor evaluation study IV-pediatric (REDS-IV-P)- domestic hubs- Phase 1
Principal Investigator: Melissa Cushing, MD
Period of Support: 04/01/2019-03/31/2020
Total Direct Costs: $35,826

JumpStart Research Career Development Program

Title: The stem cell basis of the bifurcation between adipogenic versus osteogenic lineages
Principal Investigator: Shawon Debnath, PhD (Research Associate, Matthew Greenblatt Lab)
Period of Support: 07/01/2019-06/30/2022
Total Direct Costs: $300,000

The Daedalus Fund for Innovation

Title: Development and in vitro validation of novel antibody therapeutics for vascular disorders
Principal Investigator: Teresa Sanchez, PhD
Period of Support: 04/01/2019-03/31/2020
Total Direct Costs: $100,000

National Institutes of Health (P01 Subaward)

Title: The impact of changes in chromatin architecture on cancer phenotypes and tumor progression
Principal Investigator: Giorgio Inghirami, MD
Period of Support: 06/01/2019-05/31/2020
Total Direct Costs: $121,782

US Department of Defense (Subaward)

Title: Molecular and clinical correlates with prostate-specific membrane antigen (PSMA)-targeted radionuclide therapy
Principal Investigator: Francesca Khani, MD
Period of Support: 07/01/2019-06/30/2020
Total Direct Costs: $10,331

WCM SPORE Career Enhancement Award

Title: Prostate cancers with MAPK oncogenic driver mutations: characterizations of a potentially novel and targetable molecular subclass associated with aggressive behavior
Principal Investigator: Francesca Khani, MD
Period of Support: 08/01/2019-07/31/2020
Total Direct Costs: $50,000

National Institutes of Health Research Grant (R01)

Title: Cooption of the DNA damage response for epigenetic regulation of inflammation
Principal Investigator: Steven Josefowicz, PhD
Period of Support: 12/01/2019-11/30/2024
Total Direct Costs: $1,250,000 

National Institutes of Health Research Grant (R01)

Title: Endothelial sphingolipid synthesis and tissue inflammatory response
Principal Investigator: Annarita DiLorenzo, PhD
Period of Support: 12/10/2019-11/30/2023
Total Direct Costs: $1,078,000

The Medical Centre Insurance Company (MCIC) Vermont

Title: Enhancing pathology accuracy through artificial intelligence slide review
Principal Investigator: Alain Borczuk, MD
Period of Support: 03/01/2020-12/31/2020
Total Direct Costs: $20,000

Lymphoma Research Foundation Fellowship Grant

Title: Signaling to chromatin pathways in regulation of germinal center B cell differentiation and lymphoma
Principal Investigator: Alexia Martinez De Paz (postdoc in Steven Josefowicz Lab)
Period of Support: 03/01/2020-02/28/2022
Total Direct Costs: $105,000