Newly Awarded Grants

Arthritis National Research Foundation

Title: An articular cartilage stem cell mediating cartilage regeneration for the treatment of osteoarthritis
Principal Investigator: Seoyeon Bok, PhD
Period of Support: 7/01/2023 – 6/30/2024
Total Direct Costs: $125,000

National Institutes of Health (R01 grant)

Title: Role of the CD44/Hyaluronan axis in mesenchymal prostate cancer
Principal Investigator: Maria Diaz-Meco Conde, PhD
Period of Support: 08/01/2023-07/31/2028
Total Direct Costs: $1,621,735

The American Society for Bone and Mineral Research

Title: A multi-stem cell basis for craniosynostosis
Principal Investigator: Shawon Debnath, PhD
Period of Support: 01/01/2023 – 12/31/2023
Total Direct Costs: $15,000

Manhasset Women’s Coalition Against Breast Cancer

Title: Carbon Monoxide-Based Approach for Metastatic Breast Cancer Prevention and Therapy
Principal Investigator: Yi Chieh (Nancy) Du, PhD
Period of Support: 10/25/2023 – 10/25/2025
Total Direct Costs: $86,956

Mary Kay Foundation

Title: New Approaches to Target Vertebral Metastases in Breast Cancer
Principal Investigator: Matthew Blake Greenblatt, MD, PhD
Period of Support: 7/01/2023 – 6/30/2025
Total Direct Costs: $100,000

Pershing Square Foundation

Title: A Bone to Brain Axis Controlling Alzheimer's Disease Progression
Principal Investigator: Matthew Blake Greenblatt, MD, PhD
Period of Support: 7/01/2023 – 6/30/2026
Total Direct Costs: $750,000

SPROUT award (Cornell University, Ithaca, NY)

Title: Matrix-regulation of tumor dormancy and immunoregulation in breast cancer bone metastasis
Principal Investigator: Matthew Blake Greenblatt, MD, PhD
Period of Support: 7/01/2023 – 6/30/2024
Total Direct Costs: $13,000

William Rhodes and Louise Tilzer-Rhodes Center for Glioblastoma

Title: A novel calvarial stem cell regulating glioblastoma anti-tumor immunity metastasis
Principal Investigator: Matthew Blake Greenblatt, MD, PhD
Period of Support: 7/01/2023 – 6/30/2024
Total Direct Costs: $100,000

Cornell China Center

Title: A stem Cell Basis for Vertebral Metastases
Principal Investigator: Matthew Blake Greenblatt, MD, PhD
Period of Support: 7/01/2023 – 6/30/2024
Total Direct Costs: $15,000

Children’s Tumor Foundation

Title: A skeletal stem cell basis and novel therapeutic approaches for fracture healing defects in Neurofibromatosis type 1
Principal Investigator: Sun Jun, PhD
Period of Support: 7/01/1023 – 6/30/2025
Total Direct Costs: $157,830

United States Department of Defense

Title: Elucidating the oncogenic role of EMSY in non-small cell lung cancer
Principal Investigator: Antonio Marzio, PhD
Period of Support: 01/01/2024-12/31/2026
Total Direct Costs: $374,877

National Institutes of Health (R01 grant)

Title: Elucidating mechanisms of therapy-resistance to interferon-alfa in myeloproliferative neoplasm stem cells
Principal Investigator: Seung Ha Nam, MD
Period of Support: 08/15/2023-05/31/2027
Total Direct Costs: $2,167,872

Alzheimer's Association

Title: The mechanisms driven by microglial FOXO3 underlying AD progression
Principal Investigator: Jihye Paik, PhD
Period of Support: 11/01/2023 – 10/31/2026
Total Direct Costs: $181,818

National Institutes of Health (R01 grant)

Title: DNMT and TET1 reprogramming as a targetable mechanism of resistance in advanced prostate cancer
Principal Investigator: David Rickman, PhD
Period of Support: 06/01/2023-05/31/2028
Total Direct Costs: $2,579,570

National Institutes of Health (R50 grant)

Title: Molecular mechanisms driving therapy-induced lineage plasticity
Principal Investigator: Juan Francisco Linares Rodriguez, PhD
Period of Support: 09/19/2023-08/31/2028
Total Direct Costs: $474,115

American Urological Association

Title: Characterizing the mechanistic co-operation of DNMT and EZH2 in mediating lineage plasticity in advanced prostate cancer
Principal Investigator: Richa Singh, PhD
Period of Support: 11/20/23-11/19/25
Total Direct Costs: $80,000

National Institutes of Health (R01 grant)

Title: Discovering how autophagy is sufficient to extend yeast replicative lifespan
Principal Investigator: Jessica Tyler, PhD
Period of Support: 09/01/2023 – 04/30/2028
Total Direct Costs: $1,583,845

National Institutes of Health (R01 subaward)

Title: Development of Targeted Antipseudomonal bacterial prodrugs
Principal Investigator: Lars Westblade PhD
Period of Support: 02/04/2023-01/31/2028
Total Direct Costs: $199,995

Hospital For Special Surgery T32 (T32AR071302-01) from NIH-NIAMS

Title: HSS Research Institute Rheumatology Training program
Principal Investigator: Alisha Yallowitz, PhD
Period of Support: 2/1/2023 – 1/31/2024
Total Direct Costs: $86,550

Weill Cornell Medicine Internal Grants

2023 Tri-Institutional Breakout Award

Title: Research study on skeletal stem cells
Principal Investigator: Shawon Debnath, PhD
Period of Support: 7/01/2023 – 6/30/2024
Total Direct Costs: $25,000

Primary Parents (RAPP) Award of the Mastercard Diversity-Mentorship Collaborative

Title: Identifying the skeletal adipocyte/osteoblast bipotent cell
Principal Investigator: Alisha Yallowitz, PhD
Period of Support: 7/01/2023 – 6/30/2024
Total Direct Costs: $50,000

SPORE in Prostate Cancer WCM

Title: Investigating the Role of Lipid Metabolism in Overcoming Androgen Resistance in Metastatic Castration-Resistant Prostate Cancer
Principal Investigator: Pier Nuzzo, MD PhD
Period of Support: 11/01/2023-10/31/2024
Total Direct Costs: $75,000

SPORE in Prostate Cancer WCM

Title: A Stem Cell Basis for Prostate Cancer Vertebral Metastases and Osteoblastic Lesions
Principal Investigator: Matthew Blake Greenblatt, MD, PhD
Period of Support: 11/01/23 to 10/31/24
Total Direct Costs: $75,000

Industry Sponsored Research Agreements

Hardy Diagnostics Inc.

Title: NG-Test CTX-M Multi assay
Principal Investigator: Lars Westblade, PhD
Period of Support: 7/10/2023-07/09/2024
Total Direct Costs: $22,310

Bio-Rad Laboratories

Title: Deciphering PCa Bone Metastasis Mechanisms through Targeted CTC Isolation
Principal Investigator: Mohammad Omar, MBBCH
Period of Support: 09/01/2023-08/31/2024
Total Direct Costs: $50,000

Fellowships

American Italian Cancer Foundation

Title: Investigating the role of KEAP1 in the modulation of anti-tumor immunity in non-small cell lung cancer (NSCLC)
Principal Investigator: Alessandra Ferri, PhD
Period of Support: 08/01/2023-07/31/2024
Total Direct Costs: $40,000

American Italian Cancer Foundation

Title: Generation of fully humanized murine avatars of B-ALL patients for the study of refractoriness and relapse in a bedside approach
Principal Investigator: Giovanni Medico MD
Period of Support: 08/01/2023-07/31/2024
Total Direct Costs: $40,000

American Italian Cancer Foundation

Title: Loss of Stromal Androgen Receptor (AR) Signaling Contributes to Progression in Prostate Cancer
Principal Investigator: Filippo Pederzoli, MD PhD
Period of Support: 08/01/2023-07/31/2024
Total Direct Costs: $40,000

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