Vascular and Sphingolipid Biology

Principal Investigator: 
Annarita Di Lorenzo, Ph.D.

Dr. Di Lorenzo’s laboratory is interested in two major area of research: one is to define the molecular mechanisms by which endothelial nitric oxide synthase (eNOS)-derived NO controls the endothelial barrier functions to the passage of plasma molecules and inflammatory cells.Another area of research focuses on the role of Nogo-B, belonging to the Reticulon-4 family of proteins expressed in the ER, in vascular function regulation and in cardiac hypertrophy development.

Active Projects

  • To study the role of eNOS in vascular permeability and inflammatory cell recruitment to the site of inflammation.
  • To investigate the role of Nogo-B in vascular function and cardiac hypertrophy.

Grants

PI: Dr. Annarita Di Lorenzo, Ph.D.
National Institutes of Health (NIH)

PI: Annarita Di Lorenzo, Ph.D.
Harold S. Geneen Charitable Trust Awards Program for Coronary Heart Disease Research

PI: Annarita Di Lorenzo, Ph.D.
American Heart Association (AHA)

Lab Team

Vascular and Sphingolipid Biology Lab Team

Additional Key Academic Personnel

Onorina Laura Manzo
Post Doc
olm4003@med.cornell.edu
Linda Sasset
Post Doc
lis2047@med.cornell.edu

Contact Information

Pathology and Laboratory Medicine
Weill Cornell Medical College

Annarita DiLorenzo, Ph.D.
Associate Professor of Pathology and Laboratory Medicine
and2039@med.cornell.edu

1300 York Avenue
A-610
New York, NY 10065
Phone: 
212-746-9876

Pathology & Laboratory Medicine 1300 York Avenue New York, NY 10065 Phone: (212) 746-6464
Surgical Pathology: (212) 746-2700