Laboratory of Stem Cell Aging and Cancer

Principal Investigator: 
Ji-Hye Paik, Ph.D.

We aim to understand the homeostatic mechanism of adult stem cells that is intimately linked to aging and cancer, with a hope to apply these principles for regenerative and cancer therapeutics. We employ multi-disciplinary approaches including mouse models, cell and molecular biology, metabolomics and genomics. We currently pursue PI3K-Akt-FoxO-mediated homeostatic pathway and ZNF365-dependent genomic stability.

Active Projects

  • Mechanism of Oxidative Brain Aging
  • Functional role of ZNF365 in breast cancer pathogenesis


PI: Anna (Seung Ha) Nam, M.D.
Burroughs Wellcome Fund Career Awards for Medical Scientists 

PI: Jihye Paik, Ph.D.
Irma T. Hirschl Trust - Irma T. Hirschl Career Scientist Award

PI: Jihye Paik, Ph.D.
Ellison Medical Foundation

PI: Jihye Paik, Ph.D.
Sidney Kimmel Cancer Foundation

PI: Jihye Paik, PhD
Alzheimer's Association

Lab Team

Laboratory of Stem Cell Aging and Cancer Team

Additional Key Academic Personnel

Soo Yeon Hwang Ph.D.
Post Doc

Contact Information

Ji-Hye Paik, Ph.D.
Associate Professor of Pathology and Laboratory Medicine
Weill Cornell Medical College

1300 York Avenue
New York, NY 10065

Pathology & Laboratory Medicine 1300 York Avenue New York, NY 10065 Phone: (212) 746-6464
Surgical Pathology: (212) 746-2700