Laboratory of Stem Cell Aging and Cancer

Principal Investigator: 
Ji-Hye Paik, Ph.D.

We aim to understand the homeostatic mechanism of adult stem cells that is intimately linked to aging and cancer, with a hope to apply these principles for regenerative and cancer therapeutics. We employ multi-disciplinary approaches including mouse models, cell and molecular biology, metabolomics and genomics. We currently pursue PI3K-Akt-FoxO-mediated homeostatic pathway and ZNF365-dependent genomic stability.

Active Projects

  • Mechanism of Oxidative Brain Aging
  • Functional role of ZNF365 in breast cancer pathogenesis


PI: Anna (Seung Ha) Nam, M.D.
Burroughs Wellcome Fund Career Awards for Medical Scientists 

PI: Jihye Paik, Ph.D.
Irma T. Hirschl Trust - Irma T. Hirschl Career Scientist Award

PI: Jihye Paik, Ph.D.
Ellison Medical Foundation

PI: Jihye Paik, Ph.D.
Sidney Kimmel Cancer Foundation

Lab Team

Laboratory of Stem Cell Aging and Cancer Team

Additional Key Academic Personnel

JaYoung Jang
Post Doc
Yizhe Wang
Post Doc

Contact Information

Ji-Hye Paik, Ph.D.
Associate Professor of Pathology and Laboratory Medicine
Weill Cornell Medical College

1300 York Avenue
New York, NY 10065

Pathology & Laboratory Medicine 1300 York Avenue New York, NY 10065 Phone: (212) 746-6464
Surgical Pathology: (212) 746-2700