A Prostatic Intraepithelial Neoplasia-Dependent p27Kip1 Checkpoint Induces Senescence and Inhibits Cell Proliferation and Cancer Progression.

TitleA Prostatic Intraepithelial Neoplasia-Dependent p27Kip1 Checkpoint Induces Senescence and Inhibits Cell Proliferation and Cancer Progression.
Publication TypeJournal Article
Year of Publication2024
AuthorsMajumder PK, Grisanzio C, O'Connell F, Barry M, Brito JM, Xu Q, Guney I, Berger R, Herman P, Bikoff R, Fedele G, Baek W-K, Wang S, Ellwood-Yen K, Wu H, Sawyers CL, Signoretti S, Hahn WC, Loda M, Sellers WR
JournalCancer Cell
Volume42
Issue6
Pagination1126
Date Published2024 Jun 10
ISSN1878-3686
KeywordsAnimals, Cell Cycle Checkpoints, Cell Line, Tumor, Cell Proliferation, Cellular Senescence, Cyclin-Dependent Kinase Inhibitor p27, Disease Progression, Humans, Male, Mice, Prostatic Intraepithelial Neoplasia, Prostatic Neoplasms
DOI10.1016/j.ccell.2024.05.008
Alternate JournalCancer Cell
PubMed ID38866454
Related Faculty: 
Massimo Loda, M.D.

Pathology & Laboratory Medicine 1300 York Avenue New York, NY 10065 Phone: (212) 746-6464
Surgical Pathology: (212) 746-2700