Prostate cancer: beta control your hormones.

TitleProstate cancer: beta control your hormones.
Publication TypeJournal Article
Year of Publication2010
AuthorsLoda M, Kaelin WG
JournalCancer Cell
Volume17
Issue4
Pagination311-2
Date Published2010 Apr 13
ISSN1878-3686
KeywordsBreast, Epithelial Cells, Estrogens, Humans, Male, Palliative Care, Prostatic Neoplasms
Abstract

Differentiation status influences the prognosis for localized prostate cancer. In this issue of Cancer Cell, Mak and coworkers describe a signaling pathway involving estrogen receptor beta (ERbeta) that governs whether prostate carcinoma cells maintain an epithelial phenotype or undergo epithelial-mesenchymal transition, suggesting that ERbeta would have prognostic or therapeutic value.

DOI10.1016/j.ccr.2010.03.013
Alternate JournalCancer Cell
PubMed ID20385354
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