Title | Prostate cancer: beta control your hormones. |
Publication Type | Journal Article |
Year of Publication | 2010 |
Authors | Loda M, Kaelin WG |
Journal | Cancer Cell |
Volume | 17 |
Issue | 4 |
Pagination | 311-2 |
Date Published | 2010 Apr 13 |
ISSN | 1878-3686 |
Keywords | Breast, Epithelial Cells, Estrogens, Humans, Male, Palliative Care, Prostatic Neoplasms |
Abstract | Differentiation status influences the prognosis for localized prostate cancer. In this issue of Cancer Cell, Mak and coworkers describe a signaling pathway involving estrogen receptor beta (ERbeta) that governs whether prostate carcinoma cells maintain an epithelial phenotype or undergo epithelial-mesenchymal transition, suggesting that ERbeta would have prognostic or therapeutic value. |
DOI | 10.1016/j.ccr.2010.03.013 |
Alternate Journal | Cancer Cell |
PubMed ID | 20385354 |
Related Faculty:
Massimo Loda, M.D.