Expanding the Differential Diagnosis of the Painful Nail: A Case of an Onychopapilloma with Neuroma.

TitleExpanding the Differential Diagnosis of the Painful Nail: A Case of an Onychopapilloma with Neuroma.
Publication TypeJournal Article
Year of Publication2024
AuthorsConway J, Magro CM, Lipner SR
JournalCase Rep Dermatol
Volume16
Issue1
Pagination88-93
Date Published2024 Jan-Dec
ISSN1662-6567
Abstract

INTRODUCTION: Onychopapilloma most commonly presents as longitudinal erythronychia, but diagnosis may be challenging in some cases due to varied clinical presentations. Most patients with onychopapillomas do not report associated pain but instead more commonly report functional interference.

CASE REPORT: We present a case of a 74-year-old female with a 5-year history of splitting and lifting of the right thumbnail, accompanied by nail sensitivity and intermittent painful throbbing. Clinical examination was significant for a less than 1 mm red line with distal onycholysis. Love's test and a cold test performed with ice pack were negative. X-ray of the right thumb was negative for erosion or exostosis. Nail biopsy was performed, and dermatopathology was consistent with onychopapilloma with a concomitant traumatic neuroma.

CONCLUSION: We report a case of onychopapilloma with a concomitant traumatic neuroma. Subungual neuromas are extremely rare and have not previously been associated with onychopapilloma. Our case supports the expansion of the differential diagnosis for a painful nail and demonstrates the importance of diagnostic confirmation with biopsy and histopathology.

DOI10.1159/000538087
Alternate JournalCase Rep Dermatol
PubMed ID38550795
PubMed Central IDPMC10978039
Related Faculty: 
Cynthia M. Magro, M.D.

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