| Title | Elevated soluble urokinase plasminogen activator receptor is associated with renal dysfunction in a Chlorocebus atheiops COVID-19 model. |
| Publication Type | Journal Article |
| Year of Publication | 2023 |
| Authors | Gonzalez AA, Olsen EL, Killeen SZ, Blair RV, Seshan SV, Jaimes EA, Roy CJ, Prieto MC |
| Journal | J Med Primatol |
| Volume | 52 |
| Issue | 2 |
| Pagination | 131-134 |
| Date Published | 2023 Apr |
| ISSN | 1600-0684 |
| Keywords | Animals, Biomarkers, Chlorocebus aethiops, COVID-19, Kidney Diseases, Receptors, Urokinase Plasminogen Activator, SARS-CoV-2 |
| Abstract | Increases of soluble urokinase plasminogen activator receptor (suPAR) were measured in both urine and plasma of a Chlorocebus aethiops (African green monkey; AGM) mucosal infected with SARS-CoV-2. The data indicate that elevated suPAR may be associated with renal dysfunction and pathology in the context of COVID-19. |
| DOI | 10.1111/jmp.12626 |
| Alternate Journal | J Med Primatol |
| PubMed ID | 36377612 |
| PubMed Central ID | PMC10023264 |
| Grant List | R21 AI164232 / AI / NIAID NIH HHS / United States RO1DK129299 / NH / NIH HHS / United States HHSN272201700033I / AI / NIAID NIH HHS / United States P51 OD011104 / OD / NIH HHS / United States P30 CA008748 / CA / NCI NIH HHS / United States RO1DK114321 / NH / NIH HHS / United States OD011104 / NH / NIH HHS / United States R01 DK114321 / DK / NIDDK NIH HHS / United States P30CA008748 / NH / NIH HHS / United States R01 DK129299 / DK / NIDDK NIH HHS / United States R21AI164232 / AI / NIAID NIH HHS / United States |
Related Faculty:
Surya V. Seshan, M.D.