Detection and Characterization of Influenza B Virus With Reduced Neuraminidase Susceptibility in a Stem Cell Transplant Recipient.

TitleDetection and Characterization of Influenza B Virus With Reduced Neuraminidase Susceptibility in a Stem Cell Transplant Recipient.
Publication TypeJournal Article
Year of Publication2019
AuthorsKodiyanplakkal RPriya L, Laplante JM, Westblade LF, Van Besien K, Salvatore M, St George K
JournalOpen Forum Infect Dis
Volume6
Issue12
Paginationofz493
Date Published2019 Dec
ISSN2328-8957
Abstract

Antiviral-resistant influenza viruses in the clinical environment, especially type B, are reported rarely. A stem cell transplant recipient remained influenza B positive for 2 months, despite repeated antiviral treatments. Laboratory tests demonstrated the evolution and persistence of neuraminidase inhibitor-resistant influenza B virus with a substitution at codon 119.

DOI10.1093/ofid/ofz493
Alternate JournalOpen Forum Infect Dis
PubMed ID32128335
PubMed Central IDPMC7047943
Related Faculty: 
Lars Westblade, Ph.D.

Pathology & Laboratory Medicine 1300 York Avenue New York, NY 10065 Phone: (212) 746-6464
Surgical Pathology: (212) 746-2700