Title | ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1 mutant lung cancer. |
Publication Type | Journal Article |
Year of Publication | 2021 |
Authors | Deng J, Thennavan A, Dolgalev I, Chen T, Li J, Marzio A, Poirier JT, Peng DH, Bulatovic M, Mukhopadhyay S, Silver H, Papadopoulos E, Pyon V, Thakurdin C, Han H, Li F, Li S, Ding H, Hu H, Pan Y, Weerasekara V, Jiang B, Wang ES, Ahearn I, Philips M, Papagiannakopoulos T, Tsirigos A, Rothenberg E, Gainor J, Freeman GJ, Rudin CM, Gray NS, Hammerman PS, Pagano M, Heymach JV, Perou CM, Bardeesy N, Wong K-K |
Journal | Nat Cancer |
Volume | 2 |
Issue | 5 |
Pagination | 503-514 |
Date Published | 2021 05 |
ISSN | 2662-1347 |
Keywords | Antigen Presentation, Autophagy-Related Protein-1 Homolog, Carcinoma, Non-Small-Cell Lung, Humans, Intracellular Signaling Peptides and Proteins, Lung Neoplasms |
DOI | 10.1038/s43018-021-00208-6 |
Alternate Journal | Nat Cancer |
PubMed ID | 34142094 |
PubMed Central ID | PMC8205437 |
Grant List | T32 CA009161 / CA / NCI NIH HHS / United States P30 CA016087 / CA / NCI NIH HHS / United States P01 CA117969 / CA / NCI NIH HHS / United States R01 CA166480 / CA / NCI NIH HHS / United States R01 CA205150 / CA / NCI NIH HHS / United States P50 CA058223 / CA / NCI NIH HHS / United States R01 CA219670 / CA / NCI NIH HHS / United States P30 CA008748 / CA / NCI NIH HHS / United States U01 CA233084 / CA / NCI NIH HHS / United States R01 CA076584 / CA / NCI NIH HHS / United States R01 CA215498 / CA / NCI NIH HHS / United States |
Related Lab:
Related Faculty:
Antonio Marzio, Ph.D.