Title | Spontaneous regression of a clival chordoma. Case report. |
Publication Type | Journal Article |
Year of Publication | 2020 |
Authors | Bander ED, Kocharian G, Liechty B, Tsiouris AJ, Schwartz TH |
Journal | Acta Neurochir (Wien) |
Volume | 162 |
Issue | 2 |
Pagination | 433-436 |
Date Published | 2020 02 |
ISSN | 0942-0940 |
Keywords | Aged, Chordoma, Cranial Fossa, Posterior, Female, Humans, Magnetic Resonance Imaging, Neoplasm Regression, Spontaneous, Plant Extracts, Self Administration, Skull Base Neoplasms |
Abstract | In this case report, we present a rare and previously unreported case of spontaneous regression of a histologically consistent clival chordoma. At the time of diagnosis, imaging demonstrated a T2 hyperintense and T1 isointense midline skull base mass, centered in the nasopharynx, with scalloping of the ventral clivus consistent with a chordoma measuring 3.1 × 1.9 × 3.0 cm (8.84 cm). On pre-operative imaging 2 months later, with no intervening therapy, the mass had regressed by 61.7% to a size of 2.3 × 2.1 × 1.4 cm (3.38 cm). The patient self-administered several herbal supplements and animal oils which may have contributed to tumor regression. The purpose of this report is to document this rare occurrence and provide a comprehensive description of the case details and list of the various medications, herbs, and supplements used prior to this rare event. |
DOI | 10.1007/s00701-019-04107-9 |
Alternate Journal | Acta Neurochir (Wien) |
PubMed ID | 31713157 |
Related Faculty:
Benjamin L. Liechty, M.D.