| Title | Recipient-derived EBV-positive Monomorphic Plasmacytoma Type Posttransplant Lymphoproliferative Disorder After Allogeneic Stem Cell Transplant for Severe Aplastic Anemia: A Case Report. |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Carden MA, Caltharp S, Yee ME, Haight AE, Westblade LF, Park S |
| Journal | J Pediatr Hematol Oncol |
| Volume | 38 |
| Issue | 8 |
| Pagination | e310-e314 |
| Date Published | 2016 11 |
| ISSN | 1536-3678 |
| Keywords | Anemia, Aplastic, Child, Epstein-Barr Virus Infections, Fatal Outcome, Female, Graft Rejection, Hematopoietic Stem Cell Transplantation, Humans, Lung Diseases, Lymphoproliferative Disorders, Plasmacytoma, Transplantation, Homologous |
| Abstract | Monomorphic plasmacytoma-type posttransplant lymphoproliferative disorder (PTLD) has not been reported after pediatric hematopoietic stem cell transplantation. We present a child with hepatitis-associated severe aplastic anemia who underwent an unrelated allogeneic hematopoietic stem cell transplantation and subsequently developed graft failure and an Epstein-Barr virus-positive monomorphic plasmacytoma-type PTLD of recipient origin. Despite broad-spectrum antimicrobials, weaning immunosuppression, rituximab administration, and a stem cell boost she died from complications of PTLD and a fungal pulmonary infection on day +78. |
| DOI | 10.1097/MPH.0000000000000613 |
| Alternate Journal | J Pediatr Hematol Oncol |
| PubMed ID | 27403771 |
Related Faculty:
Lars Westblade, Ph.D.