| Title | Primary anti-phospholipid antibody syndrome caused by isolated anti-phosphatidylethanolamine antibodies presenting as cryptogenic fibrosing alveolitis with recurrent pulmonary hemorrhage after single-lung transplantation. |
| Publication Type | Journal Article |
| Year of Publication | 2002 |
| Authors | Magro CM, Pope-Harman A, Moh P, Ross P |
| Journal | J Heart Lung Transplant |
| Volume | 21 |
| Issue | 11 |
| Pagination | 1232-6 |
| Date Published | 2002 Nov |
| ISSN | 1053-2498 |
| Keywords | Adult, Antibodies, Antiphospholipid Syndrome, Endothelium, Vascular, Hemorrhage, Humans, Lung, Lung Diseases, Interstitial, Lung Transplantation, Male, Phosphatidylethanolamines, Pulmonary Fibrosis |
| Abstract | A 28-year-old man underwent a single-lung transplantation for rapidly progressive usual interstitial pneumonitis. Following transplantation, primary anti-phospholipid antibody syndrome was diagnosed after a thromboembolic event and continued dyspnea. Review of his native lung and allograft tissue showed diffuse hemorrhage secondary to capillary injury, probably reflecting anti-phospholipid antibody effects on endothelia. |
| DOI | 10.1016/s1053-2498(02)00424-2 |
| Alternate Journal | J Heart Lung Transplant |
| PubMed ID | 12431499 |
Related Faculty:
Cynthia M. Magro, M.D.