Perivascular epithelioid cell tumour of the bladder.

TitlePerivascular epithelioid cell tumour of the bladder.
Publication TypeJournal Article
Year of Publication2014
AuthorsTarplin S, E Osterberg C, Robinson BD, Herman MP, Rosoff JS
JournalBMJ Case Rep
Volume2014
Date Published2014 Aug 14
ISSN1757-790X
KeywordsAdult, Cystectomy, Diagnosis, Differential, Female, Humans, Magnetic Resonance Imaging, Perivascular Epithelioid Cell Neoplasms, Urinary Bladder, Urinary Bladder Neoplasms
Abstract

A 39-year-old woman presented with a long history of pelvic pain and urinary urgency. Prior workup by her primary care doctor had been negative. The patient's gynaecologist ultimately referred her to a urologist following an ultrasound that revealed a possible bladder mass. MRI of the abdomen and pelvis demonstrated a 4 cm soft tissue lesion arising from the bladder. Cystoscopy showed an atypical mass on the anterior bladder wall, and pathological examination of the TURBT (transurethral resection of the bladder tumour) specimen revealed a perivascular epithelioid cell tumour (PEComa) with involvement of the detrusor muscle. The patient underwent a robotically assisted laparoscopic partial cystectomy. Final pathology confirmed a PEComa with negative margins. The patient had an uncomplicated postoperative course and is doing well following surgery. A surveillance cystoscopy at 6 months showed no evidence of recurrence. This case underscores the variability of clinical presentation of PEComas while proposing an appropriate method of surgical management.

DOI10.1136/bcr-2014-205500
Alternate JournalBMJ Case Rep
PubMed ID25123573
Related Faculty: 
Brian Robinson, M.D.

Pathology & Laboratory Medicine 1300 York Avenue New York, NY 10065 Phone: (212) 746-6464
Surgical Pathology: (212) 746-2700