Pediatric pustular psoriasis responsive to cyclosporine bridged to etanercept: A treatment approach.

TitlePediatric pustular psoriasis responsive to cyclosporine bridged to etanercept: A treatment approach.
Publication TypeJournal Article
Year of Publication2017
AuthorsGeorgesen C, Wildman H, Wang X, Magro C
JournalDermatol Online J
Volume23
Issue11
Date Published2017 Nov 15
ISSN1087-2108
KeywordsAdolescent, Baths, Combined Modality Therapy, Cyclosporine, Drug Therapy, Combination, Etanercept, Female, Humans, Immunosuppressive Agents, Occlusive Dressings, Psoriasis, Skin Diseases, Vesiculobullous
Abstract

Pustular psoriasis occurs rarely in children but can present with acute toxicity requiring inpatient admission. For the best approach, medical providers should have an evidence based and systematic treatment algorithm in their armamentarium. Toillustrate this point, we describe a 13-year-old girl who was admitted with generalized pustular psoriasis and who responded dramatically to "wet wrap" therapy and cyclosporine bridged to etanercept. Using this case example, we highlight the three most important considerations in any patient with new onset pustularpsoriasis: avoidance of disease complications, acute "rescue" therapy, and maintenance therapy.

Alternate JournalDermatol Online J
PubMed ID29447638
Related Faculty: 
Cynthia M. Magro, M.D. Xuan Wang, M.D., Ph.D.

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