The novel PI3K-δ inhibitor TGR-1202 enhances Brentuximab Vedotin-induced Hodgkin lymphoma cell death via mitotic arrest.

TitleThe novel PI3K-δ inhibitor TGR-1202 enhances Brentuximab Vedotin-induced Hodgkin lymphoma cell death via mitotic arrest.
Publication TypeJournal Article
Year of Publication2016
AuthorsLocatelli SL, Careddu G, Inghirami G, Castagna L, Sportelli P, Santoro A, Carlo-Stella C
JournalLeukemia
Volume30
Issue12
Pagination2402-2405
Date Published2016 12
ISSN1476-5551
KeywordsBrentuximab Vedotin, Cell Death, Drug Synergism, Enzyme Inhibitors, Heterocyclic Compounds, 4 or More Rings, Hodgkin Disease, Humans, Immunoconjugates, Mitosis, Phosphoinositide-3 Kinase Inhibitors
DOI10.1038/leu.2016.224
Alternate JournalLeukemia
PubMed ID27499137
Related Faculty: 
Giorgio Inghirami, M.D.

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