| Title | An Interactive Database for the Assessment of Histone Antibody Specificity. |
| Publication Type | Journal Article |
| Year of Publication | 2015 |
| Authors | Rothbart SB, Dickson BM, Raab JR, Grzybowski AT, Krajewski K, Guo AH, Shanle EK, Josefowicz SZ, Fuchs SM, C Allis D, Magnuson TR, Ruthenburg AJ, Strahl BD |
| Journal | Mol Cell |
| Volume | 59 |
| Issue | 3 |
| Pagination | 502-11 |
| Date Published | 2015 Aug 06 |
| ISSN | 1097-4164 |
| Keywords | Antibodies, Antibody Specificity, Databases, Genetic, HeLa Cells, Histones, Humans, Protein Array Analysis, Protein Processing, Post-Translational |
| Abstract | Access to high-quality antibodies is a necessity for the study of histones and their posttranslational modifications (PTMs). Here we debut the Histone Antibody Specificity Database (http://www.histoneantibodies.com), an online and expanding resource cataloging the behavior of widely used, commercially available histone antibodies by peptide microarray. This interactive web portal provides a critical resource to the biological research community that routinely uses these antibodies as detection reagents for a wide range of applications. |
| DOI | 10.1016/j.molcel.2015.06.022 |
| Alternate Journal | Mol Cell |
| PubMed ID | 26212453 |
| PubMed Central ID | PMC4530063 |
| Grant List | R00 CA181343 / CA / NCI NIH HHS / United States GM80896 / GM / NIGMS NIH HHS / United States GM100616 / GM / NIGMS NIH HHS / United States R01 GM100919 / GM / NIGMS NIH HHS / United States GM110058 / GM / NIGMS NIH HHS / United States CA181343 / CA / NCI NIH HHS / United States K99 GM113019 / GM / NIGMS NIH HHS / United States GM108367 / GM / NIGMS NIH HHS / United States K12 GM000678 / GM / NIGMS NIH HHS / United States F32 GM080896 / GM / NIGMS NIH HHS / United States P50 MH096890 / MH / NIMH NIH HHS / United States K99 CA181343 / CA / NCI NIH HHS / United States F32 GM108367 / GM / NIGMS NIH HHS / United States F32 GM100616 / GM / NIGMS NIH HHS / United States R01 GM110058 / GM / NIGMS NIH HHS / United States R01 GM040922 / GM / NIGMS NIH HHS / United States |
Related Faculty:
Steven Josefowicz, Ph.D.