| Title | Implementation of Molecular Surveillance After a Cluster of Fatal Toxoplasmosis at 2 Neighboring Transplant Centers. |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Isa F, Saito K, Huang Y-T, Schuetz A, N Babady E, Salvatore S, Pessin M, Van Besien K, Perales M-A, Giralt S, Sepkowitz K, Papanicolaou GA, Soave R, Kamboj M |
| Journal | Clin Infect Dis |
| Volume | 63 |
| Issue | 4 |
| Pagination | 565-8 |
| Date Published | 2016 08 15 |
| ISSN | 1537-6591 |
| Keywords | Aged, Aged, 80 and over, Early Diagnosis, Epidemiological Monitoring, Female, Humans, Male, Middle Aged, New York City, Parasitemia, Polymerase Chain Reaction, Pre-Exposure Prophylaxis, Stem Cell Transplantation, Toxoplasma, Toxoplasmosis, Transplant Recipients |
| Abstract | After a cluster of fatal toxoplasmosis among stem cell transplant recipients at 2 hospitals, surveillance with polymerase chain reaction (PCR) (blood) was instituted. Rate of reactivation among seropositive recipients was 2.2 and 16%. Parasitemia was successfully managed with preemptive treatment. For seropositive recipients unable to take prophylaxis, toxoplasma PCR surveillance should be routinely performed. |
| DOI | 10.1093/cid/ciw330 |
| Alternate Journal | Clin Infect Dis |
| PubMed ID | 27199460 |
| PubMed Central ID | PMC4967604 |
| Grant List | KL2 TR000458 / TR / NCATS NIH HHS / United States P30 CA008748 / CA / NCI NIH HHS / United States T32 AI007613 / AI / NIAID NIH HHS / United States UL1 TR002384 / TR / NCATS NIH HHS / United States |
Related Faculty:
Steven P. Salvatore, M.D.