| Title | IgG4-Related Kidney Disease in a Patient With History of Breast Cancer: Findings on 18F-FDG PET/CT. |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Krebs S, Monti S, Seshan S, Fox J, Mannelli L |
| Journal | Clin Nucl Med |
| Volume | 41 |
| Issue | 8 |
| Pagination | e388-9 |
| Date Published | 2016 Aug |
| ISSN | 1536-0229 |
| Keywords | Autoimmune Diseases, Breast Neoplasms, Carcinoma, Diagnosis, Differential, Female, Fluorodeoxyglucose F18, Humans, Immunoglobulin G, Middle Aged, Nephritis, Positron Emission Tomography Computed Tomography, Radiopharmaceuticals |
| Abstract | A 64-year-old African American woman with history of stage III breast carcinoma, 3 years after complete response to therapy, presents with progressive fatigue, increasing arthralgia, and unintentional weight loss of 15 lb in 3 months. An F-FDG PET demonstrated new diffuse FDG avidity of the renal parenchyma, new FDG-avid foci in pancreas and lungs, and new FDG-avid lymph nodes above and below the diaphragm. While a retroperitoneal lymph node biopsy was inconclusive, a kidney biopsy resulted in diagnosis of diffuse, severe, IgG4-related tubulointerstitial nephritis. Treatment with corticosteroid led to complete resolution of the symptoms and PET findings. |
| DOI | 10.1097/RLU.0000000000001252 |
| Alternate Journal | Clin Nucl Med |
| PubMed ID | 27187735 |
| PubMed Central ID | PMC4977093 |
| Grant List | P30 CA008748 / CA / NCI NIH HHS / United States |
Related Faculty:
Surya V. Seshan, M.D.