Henoch-Schonlein purpura secondary to subacute bacterial endocarditis.

TitleHenoch-Schonlein purpura secondary to subacute bacterial endocarditis.
Publication TypeJournal Article
Year of Publication2002
AuthorsGalaria NA, Lopressti NP, Magro CM
Date Published2002 Apr
KeywordsAdult, Antibodies, Antineutrophil Cytoplasmic, Antigen-Antibody Complex, Diagnosis, Differential, Endocarditis, Subacute Bacterial, Female, Fluorescent Antibody Technique, Humans, Purpura, Schoenlein-Henoch, Streptococcal Infections, Streptococcus sanguis

Henoch-Schönlein purpura (HSP), a systemic, small-vessel vasculitic syndrome, is characterized by a nonthrombocytopenic purpuric rash, arthralgia, abdominal pain, and nephritis. These signs and symptoms may occur in any order, and not all are necessary for the diagnosis. Although most common in 4- to 7-year-olds, HSP is well documented in adults and is often preceded by a history of mucosal-based infections, especially of the upper respiratory tract. We report a case of HSP that occurred coincident with the onset of subacute bacterial endocarditis (SBE) in an otherwise healtny 41-year-old white woman. The patient presented with a purpuric rash and arthralgia and was found to have left-sided streptococcal SBE. She subsequently developed abdominal pain and immune complex glomerulonephritis. The bacterial endocarditis was treated with antibiotics and mitral valve replacement, followed by a spontaneous resolution of the associated signs and symptoms of HSP.

Alternate JournalCutis
PubMed ID12080945
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