Title | Evaluation of an Immunochromatographic Assay for Rapid Detection of Penicillin-Binding Protein 2a in Human and Animal Staphylococcus intermedius Group, Staphylococcus lugdunensis, and Staphylococcus schleiferi Clinical Isolates. |
Publication Type | Journal Article |
Year of Publication | 2016 |
Authors | Arnold AR, Burnham C-AD, Ford BA, Lawhon SD, McAllister SK, Lonsway D, Albrecht V, Jerris RC, Rasheed JK, Limbago B, Burd EM, Westblade LF |
Journal | J Clin Microbiol |
Volume | 54 |
Issue | 3 |
Pagination | 745-8 |
Date Published | 2016 Mar |
ISSN | 1098-660X |
Keywords | Animals, Chromatography, Affinity, Humans, Penicillin-Binding Proteins, Peptide Synthases, Reproducibility of Results, Sensitivity and Specificity, Staphylococcal Infections, Staphylococcus intermedius, Staphylococcus lugdunensis |
Abstract | The performance of a rapid penicillin-binding protein 2a (PBP2a) detection assay, the Alere PBP2a culture colony test, was evaluated for identification of PBP2a-mediated beta-lactam resistance in human and animal clinical isolates of Staphylococcus intermedius group, Staphylococcus lugdunensis, and Staphylococcus schleiferi. The assay was sensitive and specific, with all PBP2a-negative and PBP2a-positive strains testing negative and positive, respectively. |
DOI | 10.1128/JCM.02869-15 |
Alternate Journal | J Clin Microbiol |
PubMed ID | 26677248 |
PubMed Central ID | PMC4767977 |
Related Faculty:
Lars Westblade, Ph.D.