| Title | Epistaxis and severe weakness in a patient with multiple myeloma. Therapy-related acute myeloid leukemia, pure erythroid leukemia. |
| Publication Type | Journal Article |
| Year of Publication | 2006 |
| Authors | Guo C, Inghirami G, Ibrahim S, Sen F |
| Journal | Arch Pathol Lab Med |
| Volume | 130 |
| Issue | 7 |
| Pagination | 1075-6 |
| Date Published | 2006 Jul |
| ISSN | 1543-2165 |
| Keywords | Acute Disease, Aged, 80 and over, Antineoplastic Agents, Alkylating, Epistaxis, Humans, Leukemia, Erythroblastic, Acute, Leukemia, Myeloid, Male, Melphalan, Multiple Myeloma, Muscle Weakness |
| Abstract | Therapy-related acute myeloid leukemias arise as a result of cytotoxic chemotherapy and/or radiation therapy. The most common types of acute myeloid leukemia arising in this setting are acute myeloid leukemia with maturation, and lesser numbers of acute myelomonocytic leukemia, acute monocytic leukemia, acute erythroleukemia, or acute megakaryocytic leukemia. We present a patient with multiple myeloma who was treated with melphalan and 4 years later developed acute erythroid leukemia. The morphologic diagnosis of pure erythroid leukemia developing in the setting of multiple myeloma may be challenging. |
| DOI | 10.5858/2006-130-1075-EASWIA |
| Alternate Journal | Arch Pathol Lab Med |
| PubMed ID | 16831041 |
Related Faculty:
Giorgio Inghirami, M.D.