Endoscopic diagnosis of an MRI-occult, low-grade glioma with ependymal dissemination.

TitleEndoscopic diagnosis of an MRI-occult, low-grade glioma with ependymal dissemination.
Publication TypeJournal Article
Year of Publication2015
AuthorsMargetis K, Rajappa P, Cope W, Pisapia D, Souweidane MM
JournalJ Neurosurg Pediatr
Volume16
Issue4
Pagination377-82
Date Published2015 Oct
ISSN1933-0715
KeywordsAstrocytoma, Cerebral Ventricle Neoplasms, Endoscopy, Ependyma, False Negative Reactions, Humans, Hydrocephalus, Male, Neoplasm Invasiveness, Supratentorial Neoplasms, Tectum Mesencephali, Third Ventricle, Ventriculostomy, Young Adult
Abstract

A 21-year-old man presented with triventricular hydrocephalus due to a tectal mass. He underwent an endoscopic third ventriculostomy, and multiple nodules were identified at the floor of the third ventricle intraoperatively. Surgical pathology of one of these lesions demonstrated that the tissue represented a low-grade astrocytoma. The case highlights the existing potential of neuroendoscopy to reveal neuroimaging-occult lesions, in spite of the significant advances of MRI. Furthermore, the combination of the age of the patient, the nonenhancing MRI appearance, and the multifocality of the lesions constitutes a rare and interesting neoplastic presentation within the brain. The constellation of findings likely represents dissemination of a low-grade tectal glioma via the CSF compartment.

DOI10.3171/2015.3.PEDS14444
Alternate JournalJ Neurosurg Pediatr
PubMed ID26140294
Related Faculty: 
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