| Title | To the bones: mapping the skeletal LEPR+ pool to component cell types. |
| Publication Type | Journal Article |
| Year of Publication | 2022 |
| Authors | Sun J, Greenblatt MB |
| Journal | EMBO J |
| Volume | 41 |
| Issue | 4 |
| Pagination | e110343 |
| Date Published | 2022 Feb 15 |
| ISSN | 1460-2075 |
| Keywords | Bone and Bones, Receptors, Leptin |
| Abstract | Leptin receptor-positive skeletal progenitors constitute an essential cell population in the bone, yet their heterogeneity remains incompletely understood. In this issue, Mo et al (2021) report a single-cell RNA sequencing resource that deconvolutes the pool of LEPR+ skeletal cells under homeostatic and various pathologic conditions, uncovering context-dependent contributions to diverse cell types and functions. |
| DOI | 10.15252/embj.2021110343 |
| Alternate Journal | EMBO J |
| PubMed ID | 35005783 |
| PubMed Central ID | PMC8844985 |
Related Faculty:
Matthew B. Greenblatt, M.D., Ph.D.