Acute Liver Failure Due to Echovirus 9 Associated With Persistent B-Cell Depletion From Rituximab.

TitleAcute Liver Failure Due to Echovirus 9 Associated With Persistent B-Cell Depletion From Rituximab.
Publication TypeJournal Article
Year of Publication2017
AuthorsBajema KL, Simonson PD, Greninger AL, Çoruh B, Pottinger PS, Bhattacharya R, Liou IW, Jalikis FG, Fligner CL, Rakita RM
JournalOpen Forum Infect Dis
Volume4
Issue3
Paginationofx174
Date Published2017 Summer
ISSN2328-8957
Abstract

We describe a case of fatal acute liver failure due to echovirus 9 in the setting of persistent B-cell depletion and hypogammaglobulinemia 3 years after rituximab therapy. Metagenomic next-generation sequencing further specified the etiologic agent. Early recognition may provide an opportunity for interventions including intravenous immunoglobulin and liver transplantation.

DOI10.1093/ofid/ofx174
Alternate JournalOpen Forum Infect Dis
PubMed ID28948184
PubMed Central IDPMC5604094
Grant ListT32 AI007044 / AI / NIAID NIH HHS / United States
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