| Title | Acute kidney injury due to tubular intraluminal monoclonal light chain crystals mimicking acute pyelonephritis. |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Haider M, Salvatore SP, Kaplan J, Seshan SV |
| Journal | Ren Fail |
| Volume | 36 |
| Issue | 2 |
| Pagination | 300-5 |
| Date Published | 2014 Mar |
| ISSN | 1525-6049 |
| Keywords | Acute Kidney Injury, Bence Jones Protein, Diagnosis, Differential, Humans, Immunoenzyme Techniques, Immunoglobulin lambda-Chains, Kidney Neoplasms, Kidney Tubules, Male, Middle Aged, Multiple Myeloma, Neutrophils, Pyelonephritis |
| Abstract | Tubular intraluminal inflammatory cells may be seen in kidney biopsies of patients with pyelonephritis, cell-mediated transplant rejection, autoimmune tubulointerstitial nephritis, allergic reactions, or in association with monoclonal light chain casts. When casts in a native kidney are primarily composed of granulocytes, the cause is most commonly acute pyelonephritis due to an ascending bacterial urinary tract infection. We report a 57-year-old man with acute kidney injury and an intense intraluminal neutrophil response to monoclonal lambda light chain crystal containing casts. |
| DOI | 10.3109/0886022X.2013.844643 |
| Alternate Journal | Ren Fail |
| PubMed ID | 24152144 |
Related Faculty:
Steven P. Salvatore, M.D. Surya V. Seshan, M.D.