A proposal for standardized grading of chronic changes in native kidney biopsy specimens.

TitleA proposal for standardized grading of chronic changes in native kidney biopsy specimens.
Publication TypeJournal Article
Year of Publication2017
AuthorsSethi S, D'Agati VD, Nast CC, Fogo AB, De Vriese AS, Markowitz GS, Glassock RJ, Fervenza FC, Seshan SV, Rule A, Racusen LC, Radhakrishnan J, Winearls CG, Appel GB, Bajema IM, Chang A, Colvin RB, H Cook T, Hariharan S, Hernandez LPHerrera, Kambham N, Mengel M, Nath KA, Rennke HG, Ronco P, Rovin BH, Haas M
JournalKidney Int
Volume91
Issue4
Pagination787-789
Date Published2017 04
ISSN1523-1755
KeywordsBiopsy, Disease Progression, Humans, Kidney, Predictive Value of Tests, Prognosis, Renal Insufficiency, Chronic, Severity of Illness Index, Terminology as Topic
Abstract

Chronic changes represent an important component of native kidney biopsy evaluation and have a major bearing on predicting prognosis and guiding treatment. We propose here a uniform, semiquantitative approach to assessing such changes, which include glomerulosclerosis, tubular atrophy, interstitial fibrosis, and arteriosclerosis, and we report these findings as an overall chronicity grade.

DOI10.1016/j.kint.2017.01.002
Alternate JournalKidney Int
PubMed ID28314581
Related Faculty: 
Surya V. Seshan, M.D.

Pathology & Laboratory Medicine 1300 York Avenue New York, NY 10065 Phone: (212) 746-6464
Surgical Pathology: (212) 746-2700