Tick mouth parts occlusive vasculopathy: a localized cryoglobulinemic vasculitic response.

TitleTick mouth parts occlusive vasculopathy: a localized cryoglobulinemic vasculitic response.
Publication TypeJournal Article
Year of Publication2003
AuthorsGalaria NA, Chaudhary O, Magro CM
JournalJ Cutan Pathol
Volume30
Issue5
Pagination303-6
Date Published2003 May
ISSN0303-6987
KeywordsAdult, Aged, Animals, Cryoglobulinemia, Diagnosis, Differential, Female, Humans, Insect Bites and Stings, Male, Middle Aged, Skin Diseases, Ticks, Vasculitis
Abstract

BACKGROUND: The histologic hallmark of most arthropod bite reactions is a deep, wedge-shaped perivascular and interstitial infiltrate comprising lymphocytes, neutrophils, and eosinophils.

METHODS: We present a case series of six patients in whom tick bite reactions, when examined microscopically, were found to mimic mixed cryoglobulinemic vasculitis.

RESULTS: Though different in histology, clinically these lesions were indistinguishable from typical tick bite reactions.

CONCLUSION: As five of our six biopsy specimens were found to still harbor retained tick parts, it is possible that the actual retention of tick parts was involved in evoking this localized cryoprecipitate reaction.

DOI10.1034/j.1600-0560.2003.00064.x
Alternate JournalJ Cutan Pathol
PubMed ID12753169
Related Faculty: 
Cynthia M. Magro, M.D.

Pathology & Laboratory Medicine 1300 York Avenue New York, NY 10065 Phone: (212) 746-6464
Surgical Pathology: (212) 746-2700