Spurious fibrinogen levels secondary to pyroglobulinemia in Waldenström's macroglobulinemia.

TitleSpurious fibrinogen levels secondary to pyroglobulinemia in Waldenström's macroglobulinemia.
Publication TypeJournal Article
Year of Publication1995
AuthorsCagnoni PJ, Lenzi R, Wisch N, Seremetis S, Rand JH
JournalAm J Hematol
Volume48
Issue2
Pagination126-7
Date Published1995 Feb
ISSN0361-8609
KeywordsAntibodies, Monoclonal, Bone Marrow, Chemical Precipitation, Female, Fibrinogen, Hot Temperature, Humans, Immunoelectrophoresis, Immunoglobulin lambda-Chains, Immunoglobulin M, Middle Aged, Pyroglobulins, Waldenstrom Macroglobulinemia
Abstract

We report two cases of pyroglobulinemia detected in the course of routine determination of fibrinogen levels measured by the heat-precipitation method and that led to the diagnosis of Waldenström's macroglobulinemia. The incidence of pyroglobulinemia is briefly discussed, and the potential significance of this laboratory artifact is emphasized.

DOI10.1002/ajh.2830480212
Alternate JournalAm J Hematol
PubMed ID7847327
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