Primary cardiac lymphoma treated with orthotopic heart transplantation: a case report.

TitlePrimary cardiac lymphoma treated with orthotopic heart transplantation: a case report.
Publication TypeJournal Article
Year of Publication1994
AuthorsYuh DD, Kubo SH, Francis GS, Bank A, McDonald KM, Jessurun J, Verfaillie C, Shumway SJ
JournalJ Heart Lung Transplant
Date Published1994 May-Jun
KeywordsAntineoplastic Combined Chemotherapy Protocols, Chemotherapy, Adjuvant, Female, Follow-Up Studies, Graft Rejection, Heart Neoplasms, Heart Transplantation, Humans, Lymphoma, Large B-Cell, Diffuse, Middle Aged, Neoplasm Recurrence, Local, Neutropenia

Primary lymphoma of the heart is an extremely rare tumor. It is associated with a high mortality rate because of the advanced stage of myocardial involvement at initial presentation. Conventional surgical and medical treatments have not met with much success. This article reports the first case of primary cardiac lymphoma treated with orthotopic heart transplantation. The patient had hemodynamically significant severe acute rejection, neutropenic sepsis, and tumor recurrence during the late postoperative period, illustrating the difficulties associated with concomitant immunosuppression and tumor chemotherapy. Unfortunately, the patient died after a period of remission. Our approach to the integration of immunosuppression with chemotherapy, posttransplantation follow-up, and complications is discussed.

Alternate JournalJ Heart Lung Transplant
PubMed ID8061032
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