| Title | Perivascular epithelioid cell tumor of the oral mucosa. |
| Publication Type | Journal Article |
| Year of Publication | 2005 |
| Authors | Koutlas IG, Pambuccian SE, Jessurun J, J Manivel C, Gopalakrishnan R |
| Journal | Arch Pathol Lab Med |
| Volume | 129 |
| Issue | 5 |
| Pagination | 690-3 |
| Date Published | 2005 May |
| ISSN | 1543-2165 |
| Keywords | Biomarkers, Tumor, Epithelioid Cells, Female, Humans, Immunohistochemistry, Middle Aged, Mouth Neoplasms, Periodic Acid-Schiff Reaction, Soft Tissue Neoplasms, Staining and Labeling, Treatment Outcome |
| Abstract | Perivascular epithelioid cell tumors (PEComas) are a family of tumors defined by the coexpression of melanocytic and muscle markers. Examples have been reported in many organs, soft tissues, and bone. Further expanding the list of locations, we report a case arising in the hard palate. Histologically, the tumor was composed of large elongated or epithelioid cells with granular cytoplasm. Immunohistochemically, tumor cells were positive for HMB-45, Melan A/MART-1, CD10, smooth muscle actin, desmin, and calponin. Ultrastructural examination revealed stage I melanosomes, thin filaments, and dense plaques. Recurrence has not been reported after 20 months. To our knowledge, this is the first detailed description of an intraoral PEComa. |
| DOI | 10.5858/2005-129-0690-PECTOT |
| Alternate Journal | Arch Pathol Lab Med |
| PubMed ID | 15859645 |
Related Faculty:
Jose Jessurun, M.D.