Pediatric Myelodysplastic Syndromes.

TitlePediatric Myelodysplastic Syndromes.
Publication TypeJournal Article
Year of Publication2021
AuthorsPatel SS
JournalClin Lab Med
Date Published2021 09

Pediatric myelodysplastic syndromes (MDS) comprise less than 5% of childhood malignancies. Approximately 30% to 45% of pediatric MDS cases are associated with an underlying genetic predisposition syndrome. A subset of patients present with MDS/acute myeloid leukemia (AML) following intensive chemotherapy for an unrelated malignancy. A definitive diagnosis of MDS can often only be rendered pending a comprehensive clinical and laboratory-based evaluation, which frequently includes ancillary testing in a reference laboratory. Clinical subtypes, the current diagnostic schema, and the results of more recently performed next-generation sequencing studies in pediatric MDS are discussed here.

Alternate JournalClin Lab Med
PubMed ID34304779
Related Faculty: 
Sanjay Patel, M.D., MPH

Pathology & Laboratory Medicine 1300 York Avenue New York, NY 10065 Phone: (212) 746-6464
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