Palisaded neutrophilic and granulomatous dermatitis presenting in a patient with rheumatoid arthritis on adalimumab.

TitlePalisaded neutrophilic and granulomatous dermatitis presenting in a patient with rheumatoid arthritis on adalimumab.
Publication TypeJournal Article
Year of Publication2011
AuthorsStephenson SR, Campbell SM, Drew GS, Magro CM
JournalJ Cutan Pathol
Volume38
Issue8
Pagination644-8
Date Published2011 Aug
ISSN1600-0560
KeywordsAdalimumab, Antibodies, Monoclonal, Antibodies, Monoclonal, Humanized, Antirheumatic Agents, Arthritis, Rheumatoid, Azathioprine, Dermatitis, Drug Substitution, Drug Therapy, Combination, Female, Granuloma, Humans, Middle Aged, Neutrophil Infiltration, Neutrophils, Prednisone, Skin, Treatment Outcome
Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory arthritis that can present with many unique cutaneous manifestations including palisaded neutrophilic and granulomatous dermatitis (PNGD). The authors present a case of PNGD in a RA patient on adalimumab therapy. The potential association of PNGD and adalimumab therapy is discussed as well as a review of the literature of granulomatous eruptions involving patients with RA who are receiving tumor necrosis factor-alpha inhibitor therapy.

DOI10.1111/j.1600-0560.2011.01716.x
Alternate JournalJ Cutan Pathol
PubMed ID21592182
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