Nutrient stress revamps cancer cell metabolism.

TitleNutrient stress revamps cancer cell metabolism.
Publication TypeJournal Article
Year of Publication2015
AuthorsMoscat J, Richardson A, Diaz-Meco MT
JournalCell Res
Volume25
Issue5
Pagination537-8
Date Published2015 May
ISSN1748-7838
KeywordsFood, Humans, Neoplasms, Stress, Physiological
Abstract

Efforts to identify new therapeutic targets in cancer primarily focused on oncogenes and tumor suppressor genes, and their mechanisms of action. However, there is an emerging alternative strategy that involves identification of target proteins that are not encoded by oncogenes, but are, nonetheless, required to accommodate cancer-specific stresses.

DOI10.1038/cr.2015.38
Alternate JournalCell Res
PubMed ID25828529
PubMed Central IDPMC4423079
Grant ListP30 CA030199 / CA / NCI NIH HHS / United States
R01 CA172025 / CA / NCI NIH HHS / United States
R01 CA192642 / CA / NCI NIH HHS / United States
Related Faculty: 
Jorge Moscat, Ph.D. Maria Diaz-Meco Conde, Ph.D.

Pathology & Laboratory Medicine 1300 York Avenue New York, NY 10065 Phone: (212) 746-6464
Surgical Pathology: (212) 746-2700