Title | Multicystic adenomatoid hamartoma of the pancreas: a hitherto undescribed pancreatic tumor occurring in a 3-year-old boy. |
Publication Type | Journal Article |
Year of Publication | 2008 |
Authors | Thrall M, Jessurun J, Stelow EB, N Adsay V, Vickers SM, Whitson AK, Saltzman DA, Pambuccian SE |
Journal | Pediatr Dev Pathol |
Volume | 11 |
Issue | 4 |
Pagination | 314-20 |
Date Published | 2008 Jul-Aug |
ISSN | 1093-5266 |
Keywords | Biomarkers, Cell Proliferation, Child, Preschool, Disease-Free Survival, Hamartoma, Humans, Immunoenzyme Techniques, Keratin-7, Magnetic Resonance Imaging, Male, Pancreas, Pancreatic Diseases, Pancreaticoduodenectomy |
Abstract | This report describes an unusual pancreatic tumor in a 3-year-old boy. He presented with abdominal pain secondary to pancreatitis and was found to have a complex, multicystic lesion within the head of the pancreas. He subsequently underwent a pancreatoduodenectomy. Grossly, the mass was 3 cm, multicystic, and well demarcated. Histologically, there were numerous variably sized, dilated ducts lined by tall columnar mucinous cells surrounded by a stroma that exhibited foci of cellular condensations resembling primitive pancreatic mesenchyme. Acinar and endocrine cells were often seen budding into the ducts forming "ductulo-insular bodies." As a result of its superficial resemblance to Stocker type 2 cystic adenomatoid malformation of the lung, we are proposing the name "multicystic adenomatoid hamartoma" for this lesion. |
DOI | 10.2350/07-04-0260.1 |
Alternate Journal | Pediatr Dev Pathol |
PubMed ID | 17990924 |
Related Faculty:
Jose Jessurun, M.D.