Mast cell cholangiopathy: another cause of sclerosing cholangitis.

TitleMast cell cholangiopathy: another cause of sclerosing cholangitis.
Publication TypeJournal Article
Year of Publication1995
AuthorsBaron TH, Koehler RE, Rodgers WH, Fallon MB, Ferguson SM
Date Published1995 Nov
KeywordsAged, Bile Duct Diseases, Cholangitis, Sclerosing, Female, Humans, Mastocytosis, Radiography, Ultrasonography

A 75-year-old woman with known systemic mastocytosis presented with abdominal pain, ascites, and bile duct thickening on computed tomography and ultrasonography. A liver biopsy specimen showed infiltration with mast cells. Endoscopic retrograde cholangiography showed ductal changes compatible with those found in primary sclerosing cholangitis. Brush cytology of the intrahepatic bile ducts confirmed mast cell infiltration. Systemic mastocytosis can infiltrate the biliary system, producing a cholangiopathy radiographically similar to primary sclerosing cholangitis.

Alternate JournalGastroenterology
PubMed ID7557153
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