Infectious Mimics of Inflammatory Bowel Disease.

TitleInfectious Mimics of Inflammatory Bowel Disease.
Publication TypeJournal Article
Year of Publication2023
AuthorsPanarelli NC
JournalMod Pathol
Date Published2023 Jul
KeywordsFeces, Humans, Inflammatory Bowel Diseases, Polymerase Chain Reaction

Distinguishing inflammatory bowel disease (IBD) from its mimics remains a diagnostic challenge for surgical pathologists. Several gastrointestinal infections produce inflammatory patterns that overlap with typical findings of IBD. Although stool culture, PCR, and other clinical assays may identify infectious enterocolitides, these tests may not be performed or the results may be unavailable at the time of histologic evaluation. Furthermore, some clinical tests, including stool PCR, may reflect past exposure rather than an ongoing infection. It is important for surgical pathologists to be knowledgeable about infections that simulate IBD to generate an accurate differential diagnosis, perform appropriate ancillary studies, and prompt clinical follow-up. This review covers bacterial, fungal, and protozoal infections in the differential diagnosis of IBD.

Alternate JournalMod Pathol
PubMed ID37172904
Related Faculty: 
Nicole Panarelli, M.D.

Pathology & Laboratory Medicine 1300 York Avenue New York, NY 10065 Phone: (212) 746-6464
Surgical Pathology: (212) 746-2700