Title | High-grade urothelial carcinoma: comparison of SurePath liquid-based processing with cytospin processing. |
Publication Type | Journal Article |
Year of Publication | 2009 |
Authors | Lu DY, Nassar A, Siddiqui MT |
Journal | Diagn Cytopathol |
Volume | 37 |
Issue | 1 |
Pagination | 16-20 |
Date Published | 2009 Jan |
ISSN | 1097-0339 |
Keywords | Carcinoma, Centrifugation, Histocytological Preparation Techniques, Humans, Neoplasm Staging, Urinary Bladder Neoplasms |
Abstract | There is limited literature available comparing SurePath (SP) with conventional cytospins (CS) for urine cytology specimens, especially urothelial carcinoma. In this study, urinary tract cytology cases of high-grade urothelial carcinoma were assessed on SP and CS slides. Also, the morphologic differences of high-grade urothelial carcinoma between SP and CS were evaluated on a total of 35 cases of high-grade urothelial carcinoma. SP showed that the tumor cells tend to present as three-dimensional groups and have a smaller cell size than CS. In terms of nuclear features, SP and CS were found to be comparable in morphologic assessment of the tumor cells, with CS providing a slightly better visualization. |
DOI | 10.1002/dc.20957 |
Alternate Journal | Diagn Cytopathol |
PubMed ID | 18973118 |
Related Faculty:
Momin Siddiqui, M.D.