Title | Comparison of erbium:YAG and carbon dioxide lasers in resurfacing of facial rhytides. |
Publication Type | Journal Article |
Year of Publication | 1999 |
Authors | Khatri KA, Ross V, Grevelink JM, Magro CM, Anderson RR |
Journal | Arch Dermatol |
Volume | 135 |
Issue | 4 |
Pagination | 391-7 |
Date Published | 1999 Apr |
ISSN | 0003-987X |
Keywords | Adolescent, Adult, Aged, Aged, 80 and over, Carbon Dioxide, Erbium, Female, Humans, Laser Therapy, Male, Middle Aged, Postoperative Complications, Rhytidoplasty, Skin Aging |
Abstract | OBJECTIVE: To compare the efficacy, adverse effects, and histological findings of erbium:YAG (Er:YAG) and carbon dioxide (CO2) laser treatment in removing facial rhytides. DESIGN: An intervention study of 21 subjects with facial rhytides. All participants were followed up for 6 months. The end points of the study were wrinkle improvement and duration of adverse effects. SETTING: Academic referral center. SUBJECTS: Nineteen female and 2 male volunteers with skin type I to III and wrinkle class I to III participated in the study. INTERVENTION: In all subjects, 1 side of the face was treated with a CO2 laser and other side with an Er:YAG laser. Skin biopsies were performed in 6 subjects before treatment and immediately, 1 day, 2 days, and 6 months after treatment. Observations were recorded by subjects, investigators, and a blinded panel of experts. MAIN OUTCOME MEASURES: Improvement in wrinkles and severity and duration of adverse effects. RESULTS: The CO2 laser-treated side had relatively better wrinkle improvement when evaluating all subjects (P<.03). However, in subjects receiving more than 5 passes of Er:YAG laser, improvement scores were not significantly different from those for 2 to 3 passes of CO2 laser treatment. Posttreatment erythema was noted at 2 weeks in 14 subjects (67%) on the Er:YAG laser-treated side and 20 subjects (95%) on the CO2 laser-treated side. The frequency of erythema was significantly less after Er:YAG laser treatment at 2 (P=.001) and 8 (P=.03) weeks. Hypopigmentation was seen in 1 Er:YAG-treated (5%) and 9 CO2-treated (43%) sides (chi2, P<.05). Histological evaluation showed residual thermal damage of up to 50 microm on the Er:YAG-treated side and up to 200 microm on the CO2-treated side. CONCLUSIONS: Erbium:YAG laser is safe and effective in removing facial rhytides. Subjects treated with Er:YAG laser recover more quickly from the procedure than those receiving CO2 laser treatment. |
DOI | 10.1001/archderm.135.4.391 |
Alternate Journal | Arch Dermatol |
PubMed ID | 10206045 |
Related Faculty:
Cynthia M. Magro, M.D.