Title | Babesia microti: from Mice to Ticks to an Increasing Number of Highly Susceptible Humans. |
Publication Type | Journal Article |
Year of Publication | 2017 |
Authors | Westblade LF, Simon MS, Mathison BA, Kirkman LA |
Journal | J Clin Microbiol |
Volume | 55 |
Issue | 10 |
Pagination | 2903-2912 |
Date Published | 2017 10 |
ISSN | 1098-660X |
Keywords | Animals, Antiparasitic Agents, Babesia microti, Babesiosis, Hemolysis, Humans, Ixodes, Mice, Tick-Borne Diseases, United States |
Abstract | , a zoonotic intraerythrocytic parasite, is the primary etiological agent of human babesiosis in the United States. Human infections range from subclinical illness to severe disease resulting in death, with symptoms being related to host immune status. Despite advances in our understanding and management of , the incidence of infection in the United States has increased. Therefore, research focused on eradicating disease and optimizing clinical management is essential. Here we review this remarkable organism, with emphasis on the clinical, diagnostic, and therapeutic aspects of human disease. |
DOI | 10.1128/JCM.00504-17 |
Alternate Journal | J Clin Microbiol |
PubMed ID | 28747374 |
PubMed Central ID | PMC5625376 |
Related Faculty:
Lars Westblade, Ph.D.