| Title | Woringer-Kolopp disease. A lymphomatoid hypersensitivity reaction. |
| Publication Type | Journal Article |
| Year of Publication | 1994 |
| Authors | Crowson AN, Magro CM |
| Journal | Am J Dermatopathol |
| Volume | 16 |
| Issue | 5 |
| Pagination | 542-8 |
| Date Published | 1994 Oct |
| ISSN | 0193-1091 |
| Keywords | Adult, CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Cell Nucleus, Collagen, Cytoplasm, Epidermis, Female, Histiocytes, Humans, Hypersensitivity, Infant, Langerhans Cells, Lymphatic Diseases, Receptors, Antigen, T-Cell, Skin Neoplasms, T-Lymphocytes, T-Lymphocytes, Cytotoxic, T-Lymphocytes, Helper-Inducer, T-Lymphocytes, Regulatory |
| Abstract | We report two cases of unilesional pagetoid reticulosis (Woringer-Kolopp disease). Histopathological, immunohistological, ultrastructural, and genotypic studies showed both lesions to be lymphomatoid hypersensitivity reactions, as characterized by polyclonal proliferations of T-lymphocytes; CD8+ T cytotoxic-suppressor (Tc/s) lymphocytes were predominant in one case, whereas CD4+ T helper (Th) lymphocytes were predominant in the other. The nosology of Woringer-Kolopp disease is discussed. |
| DOI | 10.1097/00000372-199410000-00017 |
| Alternate Journal | Am J Dermatopathol |
| PubMed ID | 7802169 |
Related Faculty:
Cynthia M. Magro, M.D.