Virus-associated lymphomas.

TitleVirus-associated lymphomas.
Publication TypeJournal Article
Year of Publication1999
AuthorsCesarman E, Mesri EA
JournalCurr Opin Oncol
Date Published1999 Sep
KeywordsGammaherpesvirinae, Herpesvirus 4, Human, Herpesvirus 8, Human, Human T-lymphotropic virus 1, Humans, Lymphoma

Epstein-Barr virus, Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8, and human T-cell lymphotrophic virus are viruses that are implicated in lymphoid neoplasia in humans. Their association with specific subsets of lymphomas suggests that they play an important, although not sufficient, etiologic role in their development. Current knowledge suggests that these viruses contribute to lymphomagenesis by subverting the host-cell molecular machinery to deregulate cell growth and survival. In this article, the basic information and recent developments that have contributed to our understanding of viral lymphomagenesis are reviewed.

Alternate JournalCurr Opin Oncol
PubMed ID10505767
Grant ListCA68939 / CA / NCI NIH HHS / United States
CA73531 / CA / NCI NIH HHS / United States
CA82037 / CA / NCI NIH HHS / United States
Related Faculty: 
Ethel Cesarman, M.D., Ph.D.

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