Microinvasive carcinoma of the breast: can it be diagnosed reliably and is it clinically significant?

TitleMicroinvasive carcinoma of the breast: can it be diagnosed reliably and is it clinically significant?
Publication TypeJournal Article
Year of Publication1999
AuthorsHoda SA, Prasad ML, Moore A, Hoda RS, Giri D
JournalHistopathology
Volume35
Issue5
Pagination468-70
Date Published1999 Nov
ISSN0309-0167
KeywordsBiomarkers, Tumor, Breast Neoplasms, Carcinoma in Situ, Carcinoma, Lobular, Diagnosis, Differential, Female, Humans, Immunohistochemistry, Middle Aged, Neoplasm Invasiveness
Abstract

Deciding whether in-situ breast carcinoma is associated with microinvasion is a common problem. Histological features resembling invasion can be simulated by in-situ carcinoma distorted by inflammatory and reparative changes. Having expended the effort to diagnose genuine microinvasion, just how useful is this diagnosis in planning further treatment and follow-up? In the following articles, Hoda et al. comment on the utility of immunohistochemistry in resolving uncertainty about the presence of microinvasion, and Ellis et al. critically appraise the definition of microinvasion and its clinical significance.

DOI10.1046/j.1365-2559.1999.0820a.x
Alternate JournalHistopathology
PubMed ID10583563
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Syed Hoda, M.D.

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