Meningovascular Syphilis Presenting as a Brain Mass in an Immunocompetent Male.

TitleMeningovascular Syphilis Presenting as a Brain Mass in an Immunocompetent Male.
Publication TypeJournal Article
Year of Publication2021
AuthorsPham K, Gottesdiener L, Simon MS, Trzebucki A, Maldarelli GA, Cisse B, Lieberman J, DeHaan E, Pisapia D
JournalOpen Forum Infect Dis
Volume8
Issue9
Paginationofab455
Date Published2021 Sep
ISSN2328-8957
Abstract

We present a case of a human immunodeficiency virus-negative man with syphilitic meningovascular disease with subjacent involvement of brain parenchyma leading to a mass-forming inflammatory lesion that was pathologically distinct from a typical gumma. Syphilis was diagnosed after tissue obtained from a brain biopsy demonstrated spirochetes consistent with and confirmed by 16S ribosomal RNA sequencing.

DOI10.1093/ofid/ofab455
Alternate JournalOpen Forum Infect Dis
PubMed ID34557566
PubMed Central IDPMC8454516
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