|Title||Localization of factor-VIII-related antigen in human vascular subendothelium.|
|Publication Type||Journal Article|
|Year of Publication||1980|
|Authors||Rand JH, Sussman II, Gordon RE, Chu SV, Solomon V|
|Date Published||1980 May|
|Keywords||Animals, Antigens, Basement Membrane, Endothelium, Factor VIII, Fluorescent Antibody Technique, Humans, Microbial Collagenase, Platelet Adhesiveness, Rabbits, Saphenous Vein, Umbilical Cord, Umbilical Veins|
Factor-VIII-related antigen has previously been shown to be synthesized by vascular endothelial cells. Using both an immunofluorescent staining technique and electron microscopy, we have demonstrated the presence of factor-VIII-related antigen in human vascular subendothelium. This finding may have implications in the mechanism of platelet adhesion to deendothelialized blood vessel surfaces.
Jacob H. Rand, M.D.