Title | Localization of factor-VIII-related antigen in human vascular subendothelium. |
Publication Type | Journal Article |
Year of Publication | 1980 |
Authors | Rand JH, Sussman II, Gordon RE, Chu SV, Solomon V |
Journal | Blood |
Volume | 55 |
Issue | 5 |
Pagination | 752-6 |
Date Published | 1980 May |
ISSN | 0006-4971 |
Keywords | Animals, Antigens, Basement Membrane, Endothelium, Factor VIII, Fluorescent Antibody Technique, Humans, Microbial Collagenase, Platelet Adhesiveness, Rabbits, Saphenous Vein, Umbilical Cord, Umbilical Veins |
Abstract | Factor-VIII-related antigen has previously been shown to be synthesized by vascular endothelial cells. Using both an immunofluorescent staining technique and electron microscopy, we have demonstrated the presence of factor-VIII-related antigen in human vascular subendothelium. This finding may have implications in the mechanism of platelet adhesion to deendothelialized blood vessel surfaces. |
Alternate Journal | Blood |
PubMed ID | 6244867 |
Related Faculty:
Jacob H. Rand, M.D.