| Title | Functional properties of isolated hepatocytes from ethanol-treated rat liver. |
| Publication Type | Journal Article |
| Year of Publication | 1985 |
| Authors | Schüller A, Moscat J, Diez E, Fernandez-Checa JC, Gavilanes FG, Municio AM |
| Journal | Hepatology |
| Volume | 5 |
| Issue | 4 |
| Pagination | 677-82 |
| Date Published | 1985 Jul-Aug |
| ISSN | 0270-9139 |
| Keywords | Animals, Calcium, Cell Membrane, Ethanol, Fatty Liver, Alcoholic, Glucagon, Gluconeogenesis, Insulin, Liver, Methylation, Palmitates, Phosphatidylcholines, Phospholipids, Rats, Rats, Inbred Strains, Triglycerides |
| Abstract | Gluconeogenesis and palmitate incorporation into triacylglycerols and phosphatidylcholine were measured in isolated hepatocytes from control and ethanol-treated rats. Basal gluconeogenesis and its hormonal response decreased in hepatocytes from ethanol-treated animals; palmitate incorporation into triacylglycerols increased. In ethanol-treated rat liver, 45Ca2+ uptake and methylating capacity were reduced, and the hormonal response exhibited differences in binding parameters of insulin. |
| DOI | 10.1002/hep.1840050426 |
| Alternate Journal | Hepatology |
| PubMed ID | 3894201 |
Related Faculty:
Jorge Moscat, Ph.D.