Epithelioid haemangioendothelioma of the thyroid gland: a case report and review of literature.

TitleEpithelioid haemangioendothelioma of the thyroid gland: a case report and review of literature.
Publication TypeJournal Article
Year of Publication1998
AuthorsSiddiqui MT, Evans HL, Ro JY, Ayala AG
JournalHistopathology
Volume32
Issue5
Pagination473-6
Date Published1998 May
ISSN0309-0167
KeywordsAdult, Biomarkers, Tumor, Female, Hemangioendothelioma, Epithelioid, Humans, Immunohistochemistry, Thyroid Neoplasms
Abstract

AIMS: This is a hitherto unreported case of an epithelioid haemangioendothelioma of the thyroid gland.

METHODS AND RESULTS: The patient was a 44-year-old woman who presented with a right thyroid mass. A right subtotal thyroidectomy was performed. Histologically the lesion had characteristic epithelioid and spindle cell proliferation in a background of chondromyxoid stroma. Cytoplasmic vacuolization in the epithelioid and spindle cells was present. No atypical mitotic activity or necrosis was noted. The tumour cells were positive for factor VIII-related antigen, Ulex europeus and CD 31 and were negative for cytokeratin.

CONCLUSION: The patient has been followed for 24 months and is free of recurrent and metastatic disease, which is supportive of a benign course in the thyroid gland.

DOI10.1046/j.1365-2559.1998.00384.x
Alternate JournalHistopathology
PubMed ID9639124
Related Faculty: 
Momin Siddiqui, M.D.

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