Color Doppler sonography of benign and malignant ovarian masses.

TitleColor Doppler sonography of benign and malignant ovarian masses.
Publication TypeJournal Article
Year of Publication1992
AuthorsFleischer AC, Rodgers WH, Kepple DM, Williams LL, Jones HW, Gross PR
Date Published1992 Sep
KeywordsFemale, Humans, Ovarian Diseases, Ovarian Neoplasms, Predictive Value of Tests, Ultrasonography

The use of transvaginal and transabdominal color Doppler sonography for the assessment of ovarian tumor vascularity was investigated in 62 cases of surgically excised and histologically examined ovarian masses. The modality was used to differentiate tumor neovascularity from normal arterioles (which contain smooth muscle in their media) on the basis of differences in the pulsatility observed in Doppler waveforms. Of the 25 malignant tumors in the series, 20 had low-impedance flow (pulsatility index of less than 1.0), and none had the diastolic notch seen in vessels in normal tissue. Three benign lesions, including two dermoid cysts and one tubo-ovarian abscess, also had low-impedance flow. The negative predictive value of color Doppler sonography was 98%, whereas the positive predictive value was 83%. Color Doppler sonography seems to be accurate for excluding malignancy, but some misdiagnosis may occur in cases of inflammatory and metabolically active benign masses.

Alternate JournalRadiographics
PubMed ID1529130
Related Faculty: 
William Rodgers, M.D., Ph.D.

Pathology & Laboratory Medicine 1300 York Avenue New York, NY 10065 Phone: (212) 746-6464
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